CAR T-Cell Therapy Resource Center – Quiz #1

T-lymphocyte cells are differentiated into which kind of cells that recognize peptide antigens on the surface of antigen presenting cells (APCs)?
Helper and cytotoxic cells
Co-stimulatory cells
The T-cell receptor complex
Major histocompatibility complex cells
What are the proteins expressed on T cells that provide co-stimulatory signals required for T-cell activation and survival?
Major histocompatibility complex cells
Co-stimulatory cells
Helper and cytotoxic cells
CD28 and 4-1BB
Where does the T-cell receptor complex (TCR) on both CD4+ helper T cells and CD8+ cytotoxic T cells bind to the antigen on the surface of APCs?
CD28
4-1BB
Major histocompatibility complex
Co-stimulatory cells
Co-stimulation refers to which of the following processes?
Immunologic unresponsiveness
Secondary signaling that activates T cell to respond to antigens
Immune attack evasion
Peptide antigen recognition
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